Yildirim Lab · Florida Atlantic University

RNA Folding Puzzle

Energy landscapes and computational strategies for RNA 3D structure prediction.

RNA Folding Puzzle

RNA molecules can adopt complex three-dimensional folds from sequence, and even small motifs may explore multiple competing conformations. The lab investigates computational approaches for predicting RNA 3D structures using molecular mechanics, energy landscapes, dimers, tetraloops, and experimentally informed modeling.

This section can later expand with project-specific figures, software notes, and recent publications connected to RNA tetraloops and structure prediction.

Energy landscapes

Mapping accessible conformations and transition pathways.

Structure prediction

Using physical models to connect sequence, local motifs, and 3D structure.